La Cream Duo
La Cream Duo
La Cream Duo
La Cream Duo
La Cream Duo
La Cream Duo
La Cream Duo
La Cream Duo
La Cream Duo
La Cream Duo
Clinically Proven

Clinically Proven

Up to 8 Years Younger

Up to 8 Years Younger

Retinol Replacement

Retinol Replacement

6-In-1 Product

6-In-1 Product

La Cream Duo

Skin Longevity Crème
1 fl. Oz. / 30 ml

An exclusive set of two La Creams. Keep one at home and one within reach, so your routine is never interrupted.

Ships Tomorrow
"Clinically tested on 300 women. Skin appeared up to 8 years younger in 6 weeks." Why? "biocompatible" is doing a lot of work for a one-line proof point and most customers won't know what it means.

Visible aging begins long before it appears on the surface. As the skin's natural repair and renewal functions slow, wrinkles deepen, firmness declines, radiance fades.
La Cream was formulated to address this at the source, supporting cellular energy, collagen renewal, and protection with breakthrough biotech actives at their maximum effective dose.
Every layer of aging. Addressed from within.

Most skincare is formulated as oil-in-water. Actives suspended mostly in water, sitting at the skin's surface. La Cream is built differently. As a rare inverse emulsion, 80% oil and 20% water, it mirrors your skin's own lipid barrier. This structure allows every active to be carried deeper, where it can actually work. The result isn't just a richer texture. It's a fundamentally different mechanism of action.

Each active in La Cream is selected by Dr. Natacha Bonjout, French Pharmacist, and formulated at its maximum effective dose. The concentration is clinically validated by a third-party lab, not a marketing amount.


Formulation Principle, By Dr. Bonjout:

Most creams are 90% water. La Cream isn't. Dr. Bonjout replaced the standard water base with Original Extracts™ Living Water, a mineral-rich grape water, so even the base of the formula is doing active work, restoring your skin's moisture balance from the very first application.

SIGNATURE ACTIVES

RejuveNAD™ NAD+ Youth Booster

Restores NAD+, the major molecule behind nearly every cellular process, so skin can repair and renew itself.

Matrixyl 3000™ Peptide Complex

Rebuilds collagen and elastin for visible wrinkle reduction, without retinol, without irritation.

InnerLift Calendula™ Stem Cells


Promotes deep cell regeneration and calms visible redness.

Brightenyl™ Biotech Antioxidant


Activated by your skin's microbiome to brighten tone and fade dark spots, 4× more effectively than vitamin C.


Camellia & Squalane Oils

Biocompatible lipids your skin recognizes, delivering deep nourishment without heaviness.

"Our Ultra-Clean Standard" 


There is no universal standard for clean beauty so Dr. Bonjout created one. La Cream excludes 2,200 potentially harmful ingredients, exceeding Europe's strictest regulations (which ban 1,750) and far beyond the US standard (30 ingredients banned).
No fragrance. No phenoxyethanol. No PEGs. No nanoparticles. No parabens. No mineral oils. No silicones. No talc.

Skin visibly appears up to 8 years younger with double-blind, placebo-controlled · 42 days · 300-woman reference dataset.

CELLULAR PERFORMANCE

+111% NAD+ recycling enzyme activity with RejuveNAD™ . Addresses 5 hallmarks of biological aging

−56% cellular senescence markers with Matrixyl 3000® · Reduced aging protein progerin by 27%

94% DNA protection against UV with Brightenyl™

WRINKLES & FIRMNESS

−39% deep wrinkle surface area with Matrixyl 3000® · Double-blind, placebo-controlled

+20% collagen VII production with Matrixyl 3000® · Collagen I +14.4% · Collagen XVII +15.8% · All p<0.01

+15.5% skin tonicity
+5.5% elasticity

71% showed improved dermal fiber organization

HYDRATION & RADIANCE

+67% skin hydration after 6 hours. Single application.

4× more effective than Vitamin C with Brightenyl™

Significantly reduces hyperpigmentation

Visible reduction of age spots at 28 days

WHAT WOMEN SAID

100% — skin felt softer
100% — skin appearance improved
91% — skin felt hydrated
86% — skin felt like silk
84% — skin felt more supple
82% — skin felt soothed
80% — skin appeared brighter
77% — skin tone more even

Based on a 56-day dermatological study on 44 women (ages 18–65), twice daily, under dermatological control.

RETINOL-LEVEL RESULTS. ZERO IRRITATION.

La Cream delivers retinol-level correction — firming, wrinkle reduction, texture refinement — through patented peptide technology (Matrixyl 3000®) instead of retinol. No dryness. No redness. No photosensitivity. Use morning and night, including in the sun.

THE STUDIES

3 independent clinical studies · 100+ participants · Up to 56 days under dermatological control.

I · RejuveNAD™
Double-blind, placebo-controlled · 22 women, ages 45–65
42 days twice-daily · Same concentration as La Cream

II · Matrixyl 3000®
Double-blind, placebo-controlled · 23 women + 39 men
2 months twice-daily · Same concentration as La Cream

III · La Cream (finished product)
Third-party 56-day study · 44 women, ages 18–65 - Twice daily · Under dermatological control

  • Moisturizer
  • Brightening
  • Dark Spots Corrector
  • Retinol Alternative
  • Vitamin C Alternative
  • Anti-Aging
Yuka Yuka 100/100

Every ingredient rated safe.
Verified by 60M+ users.

99.4%
naturally derived
Made in France

Formulated & manufactured
in the French Riviera.

High-Performance Actives

Each active is formulated at its optimal concentration, clinically tested and selected by Dr. Natacha Bonjout to support skin longevity, cellular repair and visible anti-aging results.
REJUVENAD™ NAD+ YOUTH BOOSTER
Enhances cellular energy and boosts NAD+ levels to revitalize skin and improve resilience against visible signs of aging.
MATRIXYL 3000™ PEPTIDE COMPLEX
Clinically proven peptides that help smooth fine lines and wrinkles while restoring firmness and elasticity.
CALENDULA STEM CELLS
Help calm irritation and redness while supporting collagen synthesis to strengthen and repair the skin structure.
BRIGHTENYL™
A next-generation antioxidant activated by the skin’s microbiome that brightens skin tone, refines pores and reduces the appearance of dark spots.
21 amino acids
Help stimulate collagen and elastin synthesis and help retain moisture.
VITIS VINIFERA (GRAPE) FRUIT WATER
Mineral-rich grape water that deeply hydrates and replenishes skin while supporting the skin’s natural moisture balance.
FULL LIST OF INGREDEINTS
VITIS VINIFERA (GRAPE) FRUIT WATER*, COCO-CAPRYLATE/CAPRATE, GLYCERIN, SQUALANE, C15-19 ALKANE, CAMELLIA OLEIFERA SEED OIL*, CAPRYLIC/CAPRIC TRIGLYCERIDE, PENTYLENE GLYCOL, LIMNANTHES ALBA (MEADOWFOAM) SEED OIL, POLYGLYCERYL-4 OLEATE, AQUA (WATER), 1,2-HEXANEDIOL, MALTODEXTRIN, POLYGLYCERYL-6 OLEATE, POLYHYDROXYSTEARIC ACID, MAGNESIUM SULFATE, MAGNESIUM STEARATE, XANTHAN GUM, POLYGLYCERYL-3 DIISOSTEARATE, SODIUM CITRATE, STEARALKONIUM HECTORITE, TOCOPHEROL, AMINOETHYLPHOSPHINIC ACID, PROPYLENE CARBONATE, CALENDULA OFFICINALIS FLOWER EXTRACT, O-CYMEN-5-OL, BUTYLENE GLYCOL, DIGLUCOSYL GALLIC ACID, SODIUM GLUCONATE, SODIUM LACTATE, HELIANTHUS ANNUUS (SUNFLOWER) SPROUT EXTRACT, CITRIC ACID, PALMITOYL TRIPEPTIDE-1, PALMITOYL TETRAPEPTIDE-7

Why La Cream Works Differently

A different formulation

A different formulation

TRADITIONAL

TRADITIONAL

LA CREAM

LA CREAM

Delivery

Sits on the skin's surface

Delivery

Carried deeper, where it works

A different type of actives

A different type of actives

TRADITIONAL

TRADITIONAL

LA CREAM

LA CREAM

Trendy Actives

Patented Actives

Retinol

Irritation, photosensitive.

NAD+ Youth Booster

+111% cellular recycling

Vitamin C

Sensitivity, instability.

Brightenyl™

4x more effective than Vitamin C

CoQ10

Antioxidant, low bioavailability.

Biotech Antioxidant

Next-gen. Microbiome-activated.

PDRN / Salmon DNA

Emerging, trend-sensitive.

Innerlift Calendula™ Stem Cells

Cellular regeneration at source

A different mechanism of action

A different mechanism of action

TRADITIONAL

TRADITIONAL

LA CREAM

LA CREAM

Surface Correction

Cellular Action

Immediate

Immediate, preventive, lasting.

THE PROOF

Skin visibly appears
up to 8 years younger in 6 weeks

3 independent clinical studies · 56 days under dermatological control · 300 women

Bonjout La Cream — Clinical testing with VISIA skin analysis

Clinically Measured Results

+111%
NAD+ cellular
recycling activity*
-39%
Deep wrinkle
reduction
+67%
skin hydration
after 6 hours***
+20%
collagen
production**
94%
DNA protection
against UV damage*
71%
improved skin fiber
density

What Women Experienced

100%
said skin
felt softer***
100%
said skin appearance
was improved***
91%
said skin feels
hydrated***
80%
said skin appeared
brighter***

*Double-blind, placebo-controlled study · Twice-daily application for 42 days · Same concentration as La Cream.

**Double-blind, placebo-controlled study · Twice-daily application for 2 months · Same concentration as La Cream.

***56-day study · 44 women · Twice daily · Under dermatological control

Dr. Bonjout explains what skin longevity actually means, and why no existing formula was doing it.

Why I Made La Cream

/1/

Dr. Natacha Bonjout

Four Signature Actives. One Formula.

/1/
RejuveNAD™ — NAD+ Youth Booster
Boosts NAD+ levels. The molecule your cells need to repair, renew, and stay resilient.
RejuveNAD™ — NAD+ Youth Booster
/2/
InnerLift Calendula™ — Plant Stem Cells
Promotes deep cell regeneration and calms visible redness while supporting collagen synthesis for stronger, more resilient skin.
InnerLift Calendula™ — Plant Stem Cells
/3/
Matrixyl 3000™ — Peptide Complex
Rebuilds collagen and elastin to visibly smooth wrinkles and restore firmness without retinol, without irritation.
Matrixyl 3000™ — Peptide Complex
/4/
Brightenyl™ — Biotech Antioxidant
Activated by your skin's own microbiome to brighten tone, fade dark spots, and refine pores. 4× more effective than vitamin C.
Brightenyl™ — Biotech Antioxidant
STEP BY STEP

How to Use

/1/

Dispense 3 pumps. Smooth upward, press in. On face, neck and décolleté. Use both morning and night and complete with Le Balm to seal.

La Cream vs. Traditional Luxury Creams

La Cream
Others
Formulation
Inverse emulsion: actives penetrate deeper
Classic emulsion: most actives sit on the surface
Approach
Works at the cellular level to slow aging
Temporary correction at the surface
NAD+ Boosting
Collagen Renewal
Retinol-free. None of the irritation, dryness, or sensitivity
Retinol causes irritation, dryness, sun sensitivity
Dark spot corrector
Brightenyl™, 4x more effective than vitamin C
Vitamin C: unstable and irritating
Plant Stem Cells
Actives
Every active at its lab-recommended maximum
Often included at sub-optimal doses
Base Ingredients
Organic Camellia oil, active grape water
Mineral oil, petrolatum, Demineralized water
Clean Standard
Fragrance-free, silicone-free, phenoxyethanol-free
Synthetic fragrance, phenoxyethanol, silicones

Our Founder Story & Craftsmanship

Excellence in every step, from ingredients to formulation

Dr. Natacha Bonjout, French Pharmacist

15 years of expertise in skin physiology. PhD in Physiology of Skin Complexion, earned at Chanel Research Labs, Paris. Analyzed over 700 active ingredients and tested more than 2,000 formulas to develop a single crème that works at the biology of aging itself.

Dermo-Cosmetic Craftsmanship

Every ingredient selected for potency, safety, and biocompatibility. Active botanicals sourced through pioneering biotechnology: plant stem cells cultivated from a single sample, regenerated infinitely in the lab. No over-harvesting. No environmental harm.

Our Ultra‑Clean Standard

We go beyond the highest European standards, removing 2,100 harmful ingredients to ensure the purest, safest formulas for your skin.

Our Ultra‑Clean Standard
Learn More

Any questions? Let us answer them

A skin longevity crème built on a rare inverse emulsion — one of the most complex structures in cosmetics. Where most creams are 80% water, La Cream is 80% oil, mirroring your skin's own lipid barrier so actives penetrate deeper instead of sitting on the surface.

Formulated by Dr. Natacha Bonjout, French pharmacist with 15 years at Chanel Research Labs, with five patented actives at their maximum effective dose. No retinol, no fragrance — and it replaces five products in one step. In clinical testing, skin appeared up to 8 years younger after 6 weeks.

Most anti-aging skincare addresses symptoms after they appear. A wrinkle forms, you treat it. A dark spot shows up, you correct it.

Skin longevity works upstream — supporting your cells so they function at their best for longer. Cellular energy, collagen renewal, oxidative protection. The visible signs of aging slow down because the biology that drives them is better supported.

La Cream was formulated to put that science to work. Not just younger-looking skin today — skin that stays resilient over time.

Because of what goes into it — and what it replaces.

The formulation is rare. An inverse emulsion is one of the most complex structures in cosmetics to stabilize. Most brands don't attempt it because the development cost and manufacturing precision are significantly higher than a standard cream.

Every active is at its full effective dose — the concentration the lab validates for real results, not a marketing amount. Patented plant stem cells, biotech antioxidants, clinical-grade peptides, NAD+ boosters. These ingredients are expensive. Dosing them properly is more expensive.

And La Cream does the work of five products: a retinol serum, a vitamin C serum, a dark spot corrector, a brightening treatment, and a moisturizer.

Purchased separately, that routine runs $400 to $600. La Cream consolidates it into one step.

At 3 pumps twice daily, one bottle lasts approximately 6 to 12 weeks. At the lower end that's around $4 per day. At the higher end, just over $2. For a formula that replaces a retinol serum, vitamin C serum, dark spot corrector, brightening treatment, and moisturizer, that's the cost of one of those products doing the work of all five.

From the first application, your skin will feel different — more hydrated, smoother, immediately more comfortable. 86% of women said their skin felt like silk after applying.

Within 2 to 4 weeks: improved radiance, more even tone, skin that looks and feels denser.

At 6 weeks: measurable results — crow's feet reduced by 12%, radiance improved by 10%, and an overall effect clinically measured as skin appearing up to 8 years younger.

Yes — all skin types, including dry, normal, combination, and sensitive.

The inverse emulsion format is inherently gentle — it mirrors your skin's own lipid structure rather than disrupting it. It nourishes without heaviness, hydrates without greasiness, and calms rather than irritates. 82% of women in clinical testing said their skin felt soothed after application.

Yes. La Cream doesn't contain retinol, but it's fully compatible if you use one.

If you do, we suggest limiting retinol to twice a week — La Cream will handle the correction on the days in between. Most customers who make the switch find they need retinol less and less over time. The Matrixyl 3000™ peptide complex delivers comparable wrinkle reduction and collagen rebuilding — without the dryness, redness, or photosensitivity.

Yes. La Cream is hypoallergenic. Clinically tested on the most sensitive skin.

No fragrance, no phenoxyethanol, no allergens. The inverse emulsion format is inherently gentler — it mirrors your skin's own lipid structure instead of disrupting it. The InnerLift Calendula™ stem cells actively calm redness and reduce inflammation. 82% of women in clinical testing said their skin felt soothed after application.If your skin has become more reactive over time, La Cream was designed with that in mind.

Yes — and this is precisely the skin La Cream was designed for.

Hormonal shifts reduce your skin's lipid production, slow collagen synthesis, and lower cellular energy. La Cream addresses all three: the inverse emulsion replenishes lipids, the Matrixyl 3000™ peptide complex supports collagen renewal, and the RejuveNAD™ booster restores cellular energy.

No fragrance, no retinol — important for skin that has become more reactive during or after menopause. Clinically tested on women ages 45 to 65 in a double-blind, placebo-controlled study. The results are measurable.

La Cream goes first. Apply 3 pumps to face, neck, and décolleté — smooth upward, press gently into the skin. Follow with Le Balm to seal and protect.

La Cream is the treatment: it targets visible aging at the cellular level. Le Balm is the seal: it reinforces the skin barrier and locks in what La Cream has done. Morning and night.

Every order includes a complimentary sample so you can try the formula before opening the full size.If La Cream isn't right for you, return the full-size product unopened for a full refund.

Less than 1% of Bonjout Beauty customers have ever requested one.

No. La Cream works beautifully on its own. But together, the two create a complete system — treatment plus protection. Many of our customers who started with Le Balm add La Cream to go deeper on aging and longevity. Many who start with La Cream add Le Balm for the barrier seal and overnight nourishment.

Because retinol causes irritation, dryness, peeling, and sun sensitivity — side effects that become harder to tolerate as skin matures. Dr. Bonjout chose Matrixyl 3000™, a peptide complex clinically proven to deliver comparable collagen-building results without those trade-offs. The wrinkle reduction without the redness.

If you currently use a retinol and want to keep it — La Cream is fully compatible. We advise you to apply retinol twice a week.

Five signature actives, each at its maximum effective dose:

RejuveNAD™ — Boosts NAD+, the molecule your cells need to repair and renew themselves.

Matrixyl 3000™ — A peptide complex that rebuilds collagen and elastin. Smooths wrinkles, restores firmness — without retinol.

InnerLift Calendula™ Stem Cells — Patented plant stem cells that calm redness and protect against oxidative stress.

Brightenyl™ — A biotech antioxidant activated by your skin's microbiome. Fades dark spots, evens tone — 4x more effective than vitamin C.

Camellia Oil & Squalane — Biocompatible lipids your skin recognizes and absorbs to rebuild the barrier.

Most creams are oil-in-water — small oil droplets floating in mostly water. La Cream is the opposite: water-in-oil, 80% oil, 20% water. This structure is rare because it's technically very difficult to stabilize.

Your skin's outermost layer is lipid-based. An inverse emulsion has a natural affinity with that barrier, so actives penetrate deeper instead of sitting on the surface. You feel the difference immediately — richer, more nourishing, but never heavy.

After cleansing, dispense 2–3 pumps. Apply to your face, neck, and décolleté. Smooth upward, then press gently into the skin. Use morning and evening — or evening only if you pair it with Le Balm in the morning.

At 3 pumps twice daily, one 30ml bottle lasts approximately 6 weeks to 12 weeks.

La Cream does not contain ingredients typically avoided during pregnancy.
However, we always recommend checking with your doctor before use.

Yes. La Cream is vegan and cruelty-free. Bonjout Beauty will never test on animals.

There is no universal standard for "clean beauty" — so Dr. Bonjout created one. La Cream is formulated without 2,100 potentially harmful ingredients, exceeding the strictest European regulations, which ban 1,750. For comparison, the US bans 30.

No fragrance. No phenoxyethanol. No PEGs. No nanoparticles. No parabens. No mineral oils. No silicones. No talc.

Trusted by Thousands